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Poison is a song by artist Alice Cooper co-written and produced by Desmond Child, released worldwide as a single in 1989 and is featured on his 18th studio album Trash. The song was one of his biggest hit singles in his home country, the United States, peaking at #7 on the singles chart, while peaking at #2 in the UK, only being held off the top spot by hit dance record, "Swing the Mood" by Jive Bunny & The Mastermixers.

The song was made available as downloadable content (as part of the Alice Cooper pack or as a single) for use in the music video game Rock Band on May 19, 2009.

There are two versions of the video to the song which shows Alice Cooper being chained to a bizarre mechanism and singing while a ghostly woman looms over him. The original video had to be censored for showings during the day, due to shots of model Rana Kennedy wearing nothing but a black thong. The portions in question were redone with her wearing a corset to cover her breasts. The video is still often played on VH1 Classic's Metal Mania.

This song is one of Alice Cooper's most well-known songs, and provided his last major mainstream hit, in 1989.

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